Weekly miscarriage rates in a community-based prospective cohort study in rural western Kenya

نویسندگان

  • Stephanie Dellicour
  • George Aol
  • Peter Ouma
  • Nicole Yan
  • Godfrey Bigogo
  • Mary J Hamel
  • Deron C Burton
  • Martina Oneko
  • Robert F Breiman
  • Laurence Slutsker
  • Daniel Feikin
  • Simon Kariuki
  • Frank Odhiambo
  • Gregory Calip
  • Andreas Stergachis
  • Kayla F Laserson
  • Feiko O ter Kuile
  • Meghna Desai
چکیده

OBJECTIVE Information on adverse pregnancy outcomes is important to monitor the impact of public health interventions. Miscarriage is a challenging end point to ascertain and there is scarce information on its rate in low-income countries. The objective was to estimate the background rate and cumulative probability of miscarriage in rural western Kenya. DESIGN This was a population-based prospective cohort. PARTICIPANTS AND SETTING Women of childbearing age were followed prospectively to identify pregnancies and ascertain their outcomes in Siaya County, western Kenya. The cohort study was carried out in 33 adjacent villages under health and demographic surveillance. OUTCOME MEASURE Miscarriage. RESULTS Between 2011 and 2013, among 5536 women of childbearing age, 1453 pregnancies were detected and 1134 were included in the analysis. The cumulative probability was 18.9%. The weekly miscarriage rate declined steadily with increasing gestation until approximately 20 weeks. Known risk factors for miscarriage such as maternal age, gravidity, occupation, household wealth and HIV infection were confirmed. CONCLUSIONS This is the first report of weekly miscarriage rates in a rural African setting in the context of high HIV and malaria prevalence. Future studies should consider the involvement of community health workers to identify the pregnancy cohort of early gestation for better data on the actual number of pregnancies and the assessment of miscarriage.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

P-219: Premature Progesterone Rise (PPR) At HCG Triggering Day Has No Correlation with ICSI Outcome: A Prospective Cohort Study

Background: The objective of this study is to evaluate the progesterone level (P Level) on the day of HCG triggering in GnRh agonist and antagonist protocols, and its correlation with clinical pregnancy rate and miscarriage rate. Premature luteinization during in vitro fertilization (IVF) was commonly happened before the introduction of GnRh analogues. High level of unwanted progesterone that i...

متن کامل

Women's attitudes towards receiving family planning services from community health workers in rural Western Kenya.

BACKGROUND Kenya ranks among the countries in Africa with high fertility rates. In order to reverse the trends in high fertility rates, there is need to increase uptake of family planning services particularly by use of community health workers (CHWs) in providing these services in rural areas. OBJECTIVE To describe the perceptions of women towards family planning service provision by CHWs in...

متن کامل

Antiretroviral Treatment for HIV in Rural Uganda: Two-Year Treatment Outcomes of a Prospective Health Centre/Community-Based and Hospital-Based Cohort

BACKGROUND In sub-Saharan Africa, a shortage of trained health professionals and limited geographical access to health facilities present major barriers to the expansion of antiretroviral therapy (ART). We tested the utility of a health centre (HC)/community-based approach in the provision of ART to persons living with HIV in a rural area in western Uganda. METHODS The HIV treatment outcomes ...

متن کامل

Housing the Urban Poor in Nigeria through Community Participation Using Lessons from Nairobi Kenya

Migration of people to urban areas from the rural areas usually comes with its challenges interms of infrastructural requirement and housing to cater for growing population. One of the challenge for the urbandwellers in Nigeria is that of adequate housing. The inability of the government to meet this demand has seen thepeople concerned seeking alternative solutions to housing need. The resultin...

متن کامل

First-trimester fetal growth restriction and the occurrence of miscarriage in rural Bangladesh: A prospective cohort study

Fetal growth restriction in early pregnancy increases the risk of adverse pregnancy outcome, which has a significant social and psychological impact on women. There is limited information related to community-based study to evaluate early indicators related to miscarriage. The aim of this study is to examine the relationship between fetal growth restriction, measured by ultrasound crown-rump le...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 6  شماره 

صفحات  -

تاریخ انتشار 2016